Presented by THE ROBERT CATHEY RESEARCH SOURCE http://www.europa.com/~rsc ------------------------------------------------------------------------- Notice: 26 January 1997 Notice of Medical Responsibility: Notice to the medical community, all medical practitioners, advisors and/or consultants to whom individuals suffering with cancer do or may resort for therapy, relief, help or advice: In view of the fact that: 1) the pancreatic enzymes carboxypeptidase, trypsin, chymotrypsin and amylase have a specificity for trophoblast, causing it to transform and degenerate, eventually destroying trophoblast (Beard, 1911; Krebs, E.T.,Bartlett, C.L, 1949); And: 2) in view of the fact that trophoblast and cancer are one and the same (Beard, J., 1902, ff.; Krebs, et al, 1949, 1950, ff.; Acevedo, H., et al, 1995, 1996); 3) pancreatic enzyme therapy is non-toxic and effective in cancer (Wolf, Maehder, Pinoci, et al. 1971; Hoefer-Janker, 1971; Titscher, Kokron, Letnansky, 1973); Therefore: It follows on the grounds of the foregoing that the utilization of pancreatic enzymes (or their potentiators) must be the preferred and first order of therapy--or in conjunction with hormone therapy and with surgery where indicated, but never surgery or hormone therapy alone--in all cancers. Furthermore, to neglect to do so, or to neglect informing the patient of this option represents a shortfall from the Hippocratic Oath, thus of ethical and responsible behavior in service to the needs of the patient. Irresponsible behavior affecting the health or welfare of another is subject to legal penalties and actions according to various Titles and Sections of U.S.Code. This notice serves to inform the public as well as the medical practitioner. Furthermore, because: 1. The chemistry of the cancer/trophoblast environment is perfused with beta-glucosidase and/or beta-glucuronidase (Perinatal Pathology, Vol. 15, 2nd Ed., Wigglesworth, Ed., 1996, p. 280; Fishman, W.H., Anlyan, A.J., J.Biol.Chem. 169:449-450, 1947; Science, 106:66-67, 1947; Fourth Int.Cancer Research Congress, 6:1034-1041, 1950) as secreted by contiguous soma in response to the cancer/trophoblast secretion of hCG-beta/CTP (Acevedo, et al, Cancer 76(8):1467-75, 1995); and because: 2. dietary nitrilosides (Laetrile) are beta-glucosides, capable of oxidation or glucuronic acid conjugation to form beta-glucuronosides specifically scissionable by beta-glycosidases (Gurchot, C., http://www.europa.com/~rsc/gurchot.htm; Sumner, Somers, Enzymes, 1943, p.73); and furthermore: 3. as scissioned molecules, the nitrilosides yield the powerful cytotoxins hydrogen cyanide and benzaldehyde with synergistic effect (Burke, McNaughton, Von Ardenne, PanMinerva Med. 13(12), Dec. 1971) to destroy the cancer/trophoblast, while being non-toxic to contiguous, non-cancerous tissues (through action of rhodanese and oxygen both of which are lacking in the cancer/trophoblast, but abundant in normal soma); Therefore, the use of nitrilosides (Laetriles) in conjunction with the above specified pancreatic enzymes (or potentiators of such) is rational, and will yield measurable benefits in destruction of cancer, and should be an obligatory primary option for every cancer patient, with the same implications of responsibility of, for and by the medical community or practitioner as hold for pancreatic enzymes alone in any cancer therapy programme or regimen. To belay recourse to these non-toxic, metabolic most-specific-means of control of cancer for any reason is unconscionable. Furthermore, to deny pancreatic enzyme/nitriloside therapy in preference of, or in substitution for any indiscriminate and/or immune suppressing cytotoxins, anti-metabolites or nitrogen-mustard derivatives, radiation, hormone therapy, anti-body therapy, or surgery alone represents irresponsible behavior, and is subject to action under various Titles and Sections of U.S.Code. According to the known facts of trophoblast and therefore of cancer: Enzyme therapy has a rational basis in cancer therapy Hormone therapy has rational basis in cancer therapy Vitamin and nutritional therapy has a rational basis in cancer therapy Surgery has a rational basis in cancer therapy Non-toxic-to-soma-chemotherapy has a rational basis in cancer therapy; or indiscriminate toxins capable of site-specific delivery have logical relevance in cancer therapy, but only as a last-resort. A more complete bibliography of above references available upon request. Entered into the Public Record via this page (http://www.europa.com/~rsc/people.htm) 26 January 1997. Please Copy and distribute. The RCRS and The Oregon Ad Hoc Committee for Medical Responsibility In Cancer Therapy --------------------------------------------------------------------------- Refs: John Beard: 1)Asexual (trophoblastic) nature of carcinoma: Lancet, June 21, 1902; 2)Asexual (trophoblastic) nature of sarcoma: Lancet, October 29, 1904; 3)Origin from a germ-cell: Lancet, June 21, 1902; amended to origin from a germ-cell embryonic in destiny, Lancet, October 29, 1904; 4)The use of pancreatic enzymes, Lancet, February 4, 1905; 5)Experimental Proof of destructive action of pancreatic enzyme on cancer: Medical Press, December 20, 1905; and British Medical Journal, January 20, 1906; 6)The place of amylopsin (amylase) in the enzyme treatment of cancer: Medical Record, New York, June 23, 1906; 7)The Enzyme Treatment of Cancer and its Scientific Basis--Collected Papers: Chatto and Windus, London, 1911; --- Ernst Krebs, et al: 1)The Toxemias in Pregnancy--The Role of The Trophoblast and The Pancreas: Medical Record, Vol. 162, No.10, October 1949; 2)The Unitarian or Trophoblastic Thesis of Cancer, Medical Record, Vol.163,No.7, July, 1950; --- Hernan Acevedo, et al: 1)Immunological Detection of Membrane-Associated Human Luteinizing Hormone Correlates with Gene Expression in Cultured Human Cancer and Fetal Cells: Endocrinology, 136(3):1034-39, 1994; 2)Human Chorionic Gonadotropin-Beta Subunit Gene Expression in Cultured Human Fetal and Cancer Cells of Different Types and Origins: Cancer 76(8):1467-75; 3)Metastatic phenotype correlates with high expression of membrane-associated complete beta-human chorionic gonadotropin in vivo: Cancer 78: 2388-2399 (1996) --- It should be pointed out that trophoblast is not fetal tissue, it does not in fact enter into the constitution of the fetus at all, but is the primary origin of the entirety of the placenta, and retains it's specific trophoblastic character in the cytotrophoblast, with syncytial trophoblast forming it's final terminal differentiation before complete destruction by the normal pancreatic enzymes secreted by mother and fetal pancreases. That these facts are now completely acknowledged does not mean they were not already established facts according to all requirements of scientific method. The literature supporting the prior establishment of these facts before the rigorous and definitive studies by Acevedo et al is abundant, and can be found in the articles by Krebs, et al in any good medical library, and copies of a few of Krebs' papers can be found on our web site. ---- People want to know what to do given these facts when they have cancer. The answer of course should be provided by your medical advisor, a specialist in the metabolic protocols based on the above facts. But a general outline may assist the individual in forming questions or providing him or herself "over the counter" programmes which have also been good for people even in the last stages of cachexia. John Beard found that proteolytic enzymes alone was dangerous. They learned from experience that AMYLASE, the carbohydrate/glycogen digesting enzyme of the pancreas was essential to pancreatic enzyme therapy for cancer. Amylase did the trick in combination with trypsin. This was before the discovery by Northrop and Kunitz of chymotrypsin (4) which Krebs found to be less toxic than trypsin in human cancer therapy (5). Beard's work is still the foundation for successful therapy, and where-ever it is deviated from, uncertain results have followed. Of course, it is because the cancer's pericellular surface is a glyco-protein that it must be acted upon by both a "glyco-digesting" enzyme and a protein digesting enzyme together. Other wise the well known eclampsia-like symptoms follow. If one were to go to an gastroenterologist, rather than an oncologist, and ask to be treated for pancreatic enzyme insufficiency, better results would be forthcoming. The expert will know that magnesium, manganese, chromium and adequate amino-acid intake are amongst the essentials for perfect functioning of the pancreas. There are pancreatic enzyme supplements available now much more potent than those available to Beard. Nature's Plus comes to mind, and Thorne Research. But no one formula has the correct ratio of amylase to proteolytic enzymes. Amylase should be double the portion of proteolytic. Vitamin A is of course an enhancer, apparently due to it's affect on the trophoblast lysosome membrane, which is more easily ruptured due to the vitamin, and so it autolyses more quickly in conjunction with action by the pancreatic enzymes. And vitamin C is logical. Nitrilosides are found abundant in seeds of all fruits with the exception of citrus. One would preferably eat organic. This is enough information to help formulate directions for one's medical expert, or to do something for oneself. ------------------------------------------------------------------------- The ROBERT CATHEY RESEARCH SOURCE. All pages Copyright _ 1996 R.S.Cathey, except where specified otherwise.