From A.J. Lanigan's book: Health in a Pill and Other Medical Myths

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A.J.Lanigan
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Columbia S.C. 29260

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An Historical Review by H. Hugh Fudenberg, M.D. John L. Tate, D.D.S.
 
     In 1906 some of the most respected physicians in the country used
trypsin (a pancreatic enzyme) successfully for inoperable cancer. Why was
it abandoned when the effectiveness was obvious? What role did medical
politics play? Will there ever be a cure for cancer? Our primary
objective is to shed light and reason to the above questions. 

Who Were Some of the Leading Physicians and Researchers in 1906 Who
Recommended Trypsin? 
     Frederick Wiggin, M.D. read before the Society of Alumni of Bellevue
Hospital, New York, NY, Case of Multiple Fibrosarcoma of the
Tongue‘Remarks on the Use of Trypsin and Amylopsin in the Treatment of
Malignant Disease.  Editorial Note: Dr. Wiggin was referred difficult and
hopeless cases because of his past successes and reputation among his
peers. Excerpts from his presentation illustrate this competence. 

      An editorial in the Journal of the American medical Association had
directed my attention to the work of Professor John Beard, lecturer in
comparative embryology in the University of Edinburgh, concerning the
origin and treatment of malignant disease, and as this case was now
considered practically a hopeless one, it was determined to test the
efficacy of the treatment. . . At the time this treatment was begun, 
there could be felt a large growth approximately two by one inch in size
at the site of the operation on the right side of the tongue. Soon after
the administration of the trypsin and the pancreatic extract had begun,
it was noticed that the tumors has apparently ceased to increase in
size. . .but when the dosage had been increased to forty minims
daily. . .there was a rapid diminution in the size of the growths,
especially in the larger one, which was perceptible from day to day,
until when the treatment was discontinued (10 days later), at the
patient's request, the patient was able to speak distinctly for the
first time. . .her general health improved greatly, as shown by her
improved looks, her more cheerful disposition, and a gain of eleven
pounds in weight. . .

     By presenting this case, inconclusive as it is, it has merely been my
wish to lay the facts before you and to call serious attention to a most
important and interesting subject, which might otherwise be overlooked,
largely on account of its unfortunate and untimely exploitation, in the
hope that further discussion of and clinical experience with trypsin and
amylopsin within a reasonable time will demonstrate beyond question that
we have our disposal a sure and efficient remedy for the treatment of 
malignant disease.(1)

William H. Rogers, M.D.; New York, New York

      A woman consulted him a year ago last July. . .complaining of an
irritable bladder, which nothing seemed to relieve. he asked her to go
with him to see Dr. Kelley, who pronounced it malignant and advised an
operation at once. She refused. By November, another surgeon, Dr. Parker
Syms, refused to operate as the growth then occupied the whole rectum. The
woman grew steadily worse until April, when Dr. Rogers began the use of
trypsin injections with halodin capsules orally. She is in as good
condition today as she was in April; the growth has positively diminished
in size. Where Dr. Rogers could apply the lotion, the growths have almost
disappeared. This it retards malignant growths, there is no doubt in his
mind. (2)

C.C. Rise, M.D.; New York, New York
      . . .He reported a case of carcinoma of the left vocal cord in a man
aged 70, in a paper which he read before the American Laryngological
Association last June. He did not remove any portion of it for microscopic
examination because he wished to notice the effect of the injection
trypsin on it. 
     Both Dr. Ferguson and Dr. Rice felt positive of the diagnosis on the
physical appearance of the growth. They administered the pancreatic
capsules for a period of two months and gave the injections of pancreatic
extract every day for thirty or forty days, in doses of from seven to ten
minims. . .after three weeks from the beginning of the treatment, the
anterior half of the growth sloughed off. . . 
     Dr. Rice saw the patient during the last week in September and found
that the entire growth had disappeared and that the vocal cord was almost
normal. . . We feel, with Professor Beard, that the doses should quickly
be made as large as the patient can judiciously bear. The unsatisfactory
cases, so far as I have observed, have been those which have come under
treatment in very advanced stages of the disease, consequently when the
general health of the patient was very much undermined. We certainly are
not giving the trypsin treatment of cancer a fair trial, unless we are
conserving the general health of the patient by the best care in the way
of good, sanitary surroundings, and healthful living. (3)

Richard A. Goeth, M.D.; San Antonio, Texas
      In every case I have treated, the tumor became inflamed as a result
of the injections, although I kept the injections as far away from the
tumor as possible. I believe the remedy will be used in much larger doses
in the future, as the trypsin itself is not poisonous and can be injected 
in indefinite doses into a healthy person. The size of the dose would 
then only be regulated by the amount of pain it produced in the tumor and 
the fever and weakness resulting from the reaction and the absorption of 
disintegrated cancer. (4)

James T. Campbell, M.D.; Chicago, Illinois
      At my request the firmly fixed, enlarged left base of the tongue and
tonsil was examined by Dr. T. Melville Hardie, Dr. George Morgenthau, and
Dr. Frederick Besley, all of whom pronounced the disease malignant and the
case inoperable. . . As the patient was failing rapidly and nothing
better could be suggested, we determined to try trypsin injections. On
August 25, 1906, 5 minims of Fairchild Bros. and Foster s injection
trypsin, diluted with 10 minims of sterilized water, were injected under
the sk in over the entire gland. . .. On September 20th, he has little or
no pain and is taking no opiate. His color is good, tongue fairly clean,
the infiltrations in the tongue, tonsil, epiglottis, and submaxillary
region have greatly decreased. He says that h e feels well and believes
himself cured. . . My belief is that the growths are carcinomutateous,
that what improvement has been brought about is entirely due to trypsin,
and that the granular cells found by Professor Zeit are degenerated cancer
cells. (5)

Who Was This Professor Beard That These Doctors Were Basing Their
Treatment of Cancer With Trypsin? 
     Professor John Beard occupied the position of lecturer in comparative
embryology at the University of Edinburgh and was the first to use trypsin
injections in the treatment of malignant growths. In 1911, Beard published
his thesis in book form, The Enzyme Treatment of Cancer. 
     Beard's trophoblast theory was complicated to explain but essentially
as Beard stated:  the true problem of cancer is simply that of the
antithesis of two digestions; that is, of two enzymes or ferments. At the
critical period, the embryo, complete in all its parts, begins to nourish
itself by an alkaline pancreatic digestion and with a ferment known as
trypsin. If this latter is wanting, the asexual generation, the
trophoblast, may become a malignant tumor of the deadliest description; if
trypsin is present, it becomes harmless and slowly degenerates. Clearly, 
then, since cancer is an irresponsible trophoblast, the ferment which 
brought about its degeneration in normal development, ought to possess 
potency when directed against the cells of a malignant tumor. It is 
important also to note that just as cancer may be found anywhere in the 
vertebrate and just as there is one mode, and one only of development for 
all the higher animals, so also the pancreas and its secretion are a 
common heritage of the higher animals. The whole story of cancer is but 
another example of that antithetic alternation which underlies all the 
phenomena of living things. 
     Beard further states:  . . .that the destructive action of the
cancerous cells is due to malignolipin, a fact that was discovered by
Petry in 1899. The theory is that trypsin is the antithesis of the cancer
enzyme malignolipin and acts upon cancer by digesting the cells and then 
the other pancreatic enzymes (amylase, lipase) dispose of the products of 
digestion. (6)

DIAGRAM OF BEARD'S THEORY FOR THE ORIGIN OF CANCER

Discussion
     Professor Beard was not a physician. In 1906, a cure for the most
feared disease known must come from the medical hierarchy NOT an
embryologist. To make matters worse, several lay magazines published
Beards Cure for Cancer.  The proper protocol had not been observed and a
crescendo of opposition began. Beard stated in a letter to the Editor of
the American medical Association Journal, Those surgeons who have
described the treatment as useless have actually never employed it. They
are really in the same logical scientific position as one of their
colleagues in Chicago, Dr. Nicholas Sem, who frankly condemns it as a
failure, while admitting that he has never tried it! (7)
     In addition to the non-physician problem, there was the purity and
viability of the trypsin formula. The porcine pancreas source required an
exacting technique. There was no refrigeration to help extend the shelf
life or freeze-dried process to protect the enzymes. There were several
formulas of trypsin on the market, that Beard later admitted, were
worthless.(8) The proper dosage and strength needed more research and
funding for the best protocol to be developed for cancer. Could the
pancreas extract of the pig be patented? Certainly not. The drug industry
was in its infancy. The money was not available if anybody could produce
it. Sound Familiar! 
     The final blow came in the form of a new technology that could be
patented, the Roentgen Ray Tube (X-ray). The treatment of cancer with
pancreatic enzymes was abandoned. Not that it didn't work; some of the
most respected surgeons in the country had used it and reported their
findings in recognized peer review journals. Normally that should have
been enough. However, because of the aforementioned reasons, this cure for
cancer was laid aside. But forgotten, NO! Dr. F. L. Shively, Sr. of
Dayton, Ohio, took up the torch for trypsin treatment.


F.L. Shively, Sr., M.D.; Dayton, Ohio
     In 1906, cancer was a rarity (5,000 to 6,000 cases for the whole
country). By 1955, over 150,000 cases were being reported‘many inoperable.
Dr. Shively, open-minded and a classical thinker, researched the medical
literature and found Beard's trypsin. Radiation was not working in the
cases he was seeing so why not trypsin? He began his cancer therapy at
Miami Valley Hospital in Dayton, Ohio. Before the F.D.A. stopped him in
1966, Dr. Shively had treated over 193 cancer victims with 4,305
intravenous trypsin enzyme injections. Most of the patients were inoperable
and terminal. Nonetheless, 12 recovered completely and were still living in
1966. The hospital staff and personnel were excited about this enzyme
treatment.  They could personally see the improvement and changes day to
day with the patients. Medical politics struck again, however, through the
F.D.A.; and Shively was forced to stop. The following case history
demonstrates a typical case reported in Shively's privately published
book:

FRANK HARTINGER 690982 APRIL, 1962
     Patient: male, age 73, entered Miami Valley Hospital 7-5-61, with a
diagnosis of carcinoma of the tongue. 
     Operation: Left Partial Glossectomy; Left Radical Neck Dissection. 
     Pathological Examination: Squamous Cell Carcinoma. 
     X-Ray Therapy: Total of 1000 R/eff to treated area. At completion of
treatment the patient showed moderate erythema in the treatment area with
poor prognosis. 
     Enzyme Therapy: Patient readmitted to MVH for Enzyme Therapy 6/2/62.
His condition‘poor and in considerable pain and discomfort. 
     The first intravenous enzyme always consists of chymotrypsin alone,
because 3% of patients react to this enzyme. Within five minutes following
insertion of needle, patient complained of pain in the tumor mass. . .the
pain lasted 20 minutes and then g radually became less. This observation
is not at all unusual; it is frequently mentioned by patients. It is
thought to indicate that chymotrypsin begins immediately to denature
cancer albumin. After six treatments, it was quite obvious to all that a
general improvement was in progress. The inflammation began to recede
from his chest rapidly‘the generalized edema was much improved. 
     The tumor masses began to fluctuate. An amber-colored fluid
(liquified cancer tissue) was repeatedly aspirated. This fluid was sent
for chemical evaluation. It occurred to the author that a polarimetric
study on liquified cancer tissue, produced by proteolytic enzymes, would
be of scientific interest, since this is perhaps the first opportunity
that presented itself. . .. John J. Lucier, Professor of Chemistry,
reported on 6/13/62 that at 30 C we find that the liquid submitted is
dextrorotatory.  One theory holds that normal tissue (crystallized
albumin) is levorotatory (-) and that cancer tissue is dextrorotatory (+).
This finding seems to support this theory. 
     Patient Dies: Severe infection finally overwhelmed the patient's
resistance in spite of antibotics, and respirations ceased 7/9/62. Mature
reflections brings the thought that the course of events may have been
different had enzyme therapy been used as the first modality instead of
the last. 
     To the end that all physicians and many more patients can avail
themselves of enzyme potentialities in early cancer cases. It now seems
altogether fitting, in my opinion, that our beloved Miami Valley Hospital
should be the first hospital in the world to do so.(9)
      Enzyme therapy to date (July, 1962) represents nine years of effort;
177 patients, and 3,952 intravenous injections; quite a major endeavor.
Honest and realistic thinking indicates that a new therapeutic principle
for treating malignancies is now within our grasp. (10)

Discussion
     Shively had now proven that cancer could be liquified in the first 24
hours with the correct combination of I.V. pancreatic enzymes a major
breakthrough. Instead of national headlines and acknowledgement, an F.D.A.
reprimand and an order from the government STOP! The cure for cancer
would come from the newly formed National Institute of Health. And
besides, President Nixon would soon declare a War on Cancer.  Shrively s
dramatic addition to the enzyme protocol for cancer would not go unnoticed
however. Others were waiting eagerly for the good news and documented
proof. 

The Dentist Who Dared One Answer to Cancer William Donald Kelley, D.D.S.
(Winthrop, Washington)
     William Donald Kelley, orthodontist and self-educated nutritionist,
lay in the surgical recovery room. His surgeon had just told him the bad
news pancreatic cancer that had spread to the liver. They had no choice
but to close him up. A biopsy was not necessary. He had 3 months to live. 
Too make matters worse, his wife had allowed his life insurance policy to 
lapse. It was 1967 and the orthodox cure for pancreatic cancer was 0.5%. 
If there was an alternative in this new field of nutrition and alternat 
ive, holistic approaches, then the timing was perfect. He had little 
choice but to heal himself. 
     Kelley placed himself on a rigorous vegetarian diet, the new
freeze-dried pancreatic enzymes every two hours by mouth, detoxification
of the liver through coffee enemas, and the nauseating intake of chewed
raw liver. He began to get better day by day . In three months, he was
back at his orthodontic practice. In 6 months, he was completely well! His
doctors called it spontaneous remission, of course. But Kelley knew
better. He could no longer practice orthodontics. He was hooked on this
new therapy and its enormous implication. His book, One Answer to Cancer,
became a National best seller in the alternative world. Kelley would
devise over 10,000 nutritional programs for cancer victims in the next 18
years. His metabolic typing concept would be the fir st time anyone would
bring all the pieces of the puzzle together regarding individuality why
one man s meat is another man's poison.  It may yet prove to be the most
valuable contribution to the holistic healing concepts.
 Kelley's fame was spreading. In 1981, Steve McQueen was dying of
mesothelioma, a rare lung cancer. He had been given three months to live a
period with which Kelley was familiar. Kelley knew the risk. His recently
established relationship with a clinic in Mexico was barely in existence.
He would be blamed for anything that went wrong and it did. Although Steve
McQueen was recovering (an X-ray of the lungs and blood tests proved it),
he died of an embolus to the heart following surgery to remove a two
pound tumor pressing on his bladder. His surgeon, Dr. Santos Vargas, in
his operative notes remarked how easily the dead tumor was lifted out.  In
addition, a contraindication for general anesthesia is lung cancer
involving over 50% of both lungs which McQueen had documented at a
California hospital six months earlier. To a reasonable thinking person,
the facts were obvious. The National media, however, were not looking for
facts; they were looking for blood. Kelley fit the bill. In William F.
Holmes McQueen, p.210: 
          Stateside doctors challenged Kelley to prove these claims, and
he obliged by releasing data representing independent confirmation. Blood
samples from McQueen had been submitted on two occasions (in early August
and late October) to Emil Schandl, Ph.D., Director of the C.A. Laboratory 
Center in Dania, Florida. Schandl conducted extensive laboratory tests on 
the blood and was amazed at the results.  Our tests allow us to monitor a 
patient s response to therapy, Schandl said.  This applies to what ever 
type of treatment the patient receives chemotherapy, radiation or, in 
this case, metabolic therapy. The first time the patient was tested, he 
had three markers that were quite abnormal‘very abnormal. But when I 
tested his blood the second time, some eight weeks later, all the markers 
were negative‘that is to say, in the normal range. It was totally 
unbelievable for me to see such a tremendous clinical biochemical 
improvement.  (11)
       McQueen's case did invoke a different response by the medical
profession to the deadly lung cancer (mesothelioma). Dr. Steven Levin, of
the Department of Occupational Medicine at Mount Sinai School of Medicine
in New York, declared:  There is evide nce that the individual s own
immune system can retard development of mesothelioma as long as that
system remains effective. However, once the body's defense breaks down,
the disease grows unchecked. (12)

Discussion
     Kelley, a meticulous, dedicated, innovative thinker, had gambled and
lost. His genius was not in any new discovery but in organization, common
sense, and the courage to pioneer a new concept holistic individuality
through immune stimulation and rebui lding. The body and mind could heal
itself under the proper conditions. His program provided those conditions. 
     The I.R.S. stepped into the picture. Sound Familiar! Between
government harassment, attorney s bills, and 20-hour work days, Kelley had
to step aside. He would retire to the mountains of Pennsylvania where he
still resides as of this writing. Kelley did ask Nicholas Gonzalez, M.D.,
to investigate his work, however, and pancreatic enzymes, immune therapy,
and Kelley's concepts began to inspire a new beginning.

The introduction to Dr. Gonzalez can be best explained and summarized
in a letter he wrote to Whom it May Concern in November 1986. 
                189-36 45th Road
                Flushing, New York 11358
                November 10, 1986
To whom it may concern: 
     I am writing in reference to the case of Dr. Carol Morrison, and the
therapy she has been using as treatment for her cancer. I myself am a
medical doctor and cancer researcher. For the past five years, under the
direction of Dr. Robert A. Good, one of the world's foremost
immunologists, I have been investigating the nutritional therapies
developed by Dr. William Donald Kelley. 
     After an exhaustive reveiw [sic] of 10,000 seriously ill patients
treated with Dr. Kelley, we have found that his methods represent a
potentially powerful tool in the treatment of advanced cancer. I recently
completed an extended report of our findings, which we hope to have
published within the next year. 
     Dr. Morrison first came to be evaluated by our research group on
December 11, 1984, when we were based at the University of Oklahoma. She
had been diagnosed some months previously with metastatic breast cancer,
had undergone a mastectomy, and had in August of 1984, with few options,
decided to pursue the Kelley program. 

Discussion
     Dr. Gonzalez report has not been published to this date. The
peer-review publications gave many excuses‘none were logical to the common
sense, independent thinker. The insurance companies have expressed
interest, however. They are interested in survivability and cost. Robert
Maver, F.S.C., Vice President of Research at Mutual Benefit Group
Operations located in Kansas City, Missouri, has taken an interest in Dr.
Gonzalez treatment and has published a report on his work in the
professional insurance journal, On the Risk. In an interview, Mr. Maver 
said, The longer I look at his work, the more astonished I am.  Maver 
hopes to obtain funding for a controlled research program to confirm the 
initial findings.  Most studies look at tumor shrinkage; we want to look 
at survival rate that's what counts. (13) Kelley's cancer patients were 
surviving much longer at one-tenth of the cost. 
     Gonzalez, on Park Avenue, New York, who is practicing his version of
the Kelley Program, claims an 80% survival rate for all forms of cancer.
For example, pancreatic cancer under orthodox treatment has a survival
rate of 0.5%.(14) Most cases are dead in three months (e.g. Michael 
Landon). Kelley had six cases past five years including himself. Gonzalez 
feels he certainly could not do worse than the present orthodox history 
of 0.5% survival and death in three months. A pilot project of ten cases 
with the support of the N.I.H. would certainly be in order. 
Realistically, however, the chances are poor. Nonetheless, as medical 
costs escalate ($912 billion per year), alternatives are being seriously 
studied. The new office in Washington, D.C., Medical Alternatives, and 
funded with $2 million of the taxpayers monies, is now ready to 
investigate any serious alternative that meets certain criteria. 
Pancreatic enzymes and the Kelley Program (Gonzalez report) will 
hopefully be part of this investigation. If, as the poet says, timing is 
everything, then the time is now. 

Conclusion
     John Beard's trophoblastic theory of cancer has been debated for over
85 years. The New York Academy of Sciences in 1959 at their August meeting
stated: 
         The hypothesis that cancer and trophoblast are identical has also
been urged (Krebs, et al., 1950). . . .[A]s a thesis in the sense of a
conclusion or proposition to be defended in argument it contains serious
logical faults. . . The relation bet ween trophoblast and cancer remains a
stimulating but unanswered question. (15)
       If the hypothesis is correct, then trophoblastic and cancerous
invasions resemble each other in depending on high metabolism and
glycolysis, but they differ in that the respiratory insufficiency of
cancers is permanent, intrinsic, and not subject t o external control;
whereas, the respiratory inadequacy of the trophoblast is temporary and
extrinsic, being normally relieved by the trophoblast s physiological
objective, the maternal circulation. . . The glycolytic ability of
trophoblast may be a clue to the unusually rapid course of
choriocarcinoma. . .cancers are believed to originate from other tissues
by a partial injury to respiration followed by a latent period to select
and build up a population of cells with accentuated glycolytic ability.
(16)

        The invasiveness of the trophoblast in pregnancy remained a
mystery even to the prestigious New York Academy of Sciences. Beard's
theory is never mentioned that during the third month of pregnancy the
degeneration of the trophoblast is caused by the addition of the fetal
proteolytic enzymes to those of the mother."(17)
     Wiggin, Rogers, Rice, and Campbell were all competent M.D.s well
trained to evaluate clinical medical problems. They were not that
interested in theories by research scientists. If it sounded reasonable,
would not cause additional harm, offered hope to an otherwise hopeless
situation why not? They reported their observations to the most respected
peer review journal of that day the Journal of the American medical
Association. 
     There was no doubt in their minds that pancreatic enzymes worked to
destroy cancer. Was it discarded because of the new technology the X-ray?
Was the fact that the porcine source of the pancreatic enzyme could not be
patented an obstacle? In 1906, th ere were no double-blind studies or
F.D.A. regulations with which to comply. It was much easier then to use a
new drug that was safe and effective. Pancreatic enzymes were cast aside
as a novelty, a curiosity. Was it too simple and inexpensive for such a
terrible disease? 
     F. L. Shively of Dayton, Ohio, picked up the torch and showed
clinically that the combination of pancreatic enzymes in an intravenous
solution would begin liquifying a tumor in 24 hours a major breakthrough.
But was it too fast? The absorption of tox ins from the tumors were
producing septicemia and infection. The science of detoxification was not
yet playing a major role in cancer therapy. The role of diet and special
food supplements to support the immune system was in the future.
Nonetheless, Shive ly s contribution was a major step in the non-toxic,
holistic approach to healing cancer. 
     Kelley, a dentist, healed himself from pancreatic cancer, the
deadliest of tumors (three month average survival) in 1967. He applied
massive amounts of pancreatic enzymes, diet, special food supplements, and
a comprehensive detoxification program. There would be five other cases
who followed the same program and healed themselves that Gonzalez would
document in his 1988 report. If Steve McQueen had lived through his
surgery, the Kelley Program would probably be an accepted alternative to
the present orthodox therapy. Kelley s major contribution was metabolic
typing and a comprehensive holistic approach to cancer that put the immune
system in a self-healing position. 
     Gonzalez is practicing his interpretation of Kelley s work in New
York, NY, and claiming an eighty percent success rate with all forms of
cancer. His 5-year report as of this date has not been published. 
     In the Physician s Desk Reference (PDR) pancreatic enzymes are listed
mainly for cystic fibrosis and pancreatic deficiency disease? or more
plainly stated is cancer simply a degenerative deficiency disease? 
    With the renewed interest in lowering medical costs and using more
natural approaches to self-healing and individual responsibility, perhaps
the time has come to bring pancreatic enzymes to its proper position and
emphasis in immunotherapy and the non -toxic natural self-healing concept. 

The Future Role of Pancreatic Enzymes in Immunotherapy

     In Cancer Facts and Figures 1993, published by the American Cancer
Society, Treatment of cancer is now being tried by surgery, radiation,
radioactive substances, chemicals, hormones, and immunotherapy. (18)
     Immunotherapy holds the hope of enhancing the body s own
disease-fighting systems to control cancer. Immunotherapy is our choice
for the treatment of the future. It is the belief of many scientists,
physicians, and virologists that cancer will always be with us. The 
cancer virus is part of the animal genome. It is our immune systems that 
keep it in check and under control. Chemotherapy and radiation are 
failing simply because of the communication gap between oncology and 
immunology. The powerful drug -institutional-grant approach that insists 
on its patentable drug for its existence will protect its position. 
Immunotherapy must come from the grass-roots primary physician and the 
alternative health practitioner. Do we have any other choice? Immuno-
Therapeutic Research Foundation is ready for the new beginning. Hugh 
Fudenberg and immunologists like him have proven that the body/mind's
self-healing concepts through the immune system is our most powerful
weapon. 
     There are no silver bullets only a rigorous, comprehensive program
that involves work and time to rebuild the immune system. It is certainly
not for everyone. Individual responsibility is a must and is the central
focus in the stimulation and rebuild ing of the immune system. 
     H. Hugh Fudenberg, M.D. one of the world s leading immunologists and
the pioneer developer of Transfer Factor (TF), the immune extract that is
revolutionizing approaches to what has been thought of as incurable
diseases, stated: 
         I ve known about Alpha-chymotrypsin in de-shielding tumor cells
for 15 years, but I did not know about Shively's work or the clinical
cases of Gonzalez and Kelley. I see no reason why pancreatic enzymes would
not work in a total approach toward immune surveillance and control. If
the immune cells can outnumber the cancer cells 40-1 in hard tumors and
20-1 in soft tumors, we have won the battle. According to my research, we
are making TF specific for each cancer. The killer cells will be armed 
with a laser gun instead of a 22-rifle. But it takes numbers to win.
Chemotherapy and radiation kill everything the good and the bad not very
smart. With pancreatic enzymes, diet, detoxification, and immune biologics
like TF, we can win with numbers. I have every confidence in success. 
  
BIBLIOGRAPHY
1.  Wiggin, F.H., Case of Multiple Fibrosarcoma of the Tongue, with
    Remarks on the Use of Trypsin and Amylopsin in the Treatment of
    Malignant Disease.  J. Am. Med. Assoc., 12/15/06; 47:2003-8.
2.  Rogers, W.H.  Case History-Rectal Cancer.  J. Am. Med. Assoc.,
    12/15/06; 47:2008.
3.  Rice, C.C.  Treatment of Cancer of the Larynx by Subcutaneous
    Injection of Pancreatic Extract (Trypsin).  Medical Record,
    11/24/06;4:812-6.
4.  Goeth, Richard A.  Pancreatic Treatment of Cancer, with Report
    of a Cure.  J. of Am. Medical Assn., 3/23/07; p.1030.
5.  Campbell, J.T.  Trypsin Treatment of a Case of Malignant
    Disease.  J. of Am. Medical Assn., 1/19/07; 48:225-6.
6.  Beard, J.  The Scientific Criterion of a Malignant Tumor.
    Medical Record, 1/8/07; p.24-5.
7.  Ibid.
8.  Ibid.
9.  Shively, F.L. Multiple Proteolytic Enzyme Therapy of Cancer.
    Dayton, Johnson-Watson, 1969.
10. Ibid.
11. William F. Holmes, McQueen, p.210.
12. Quote from Dr. Steven Levin.
13. Quote from Robert Maver, F.S.C., Vice President of Research at
    Mutual Benefit Group Operations located in Kansas City, Missouri.
14. Gonzalez Report (unpublished).
15. B”ving, Bent G.  The Biology of Trophoblast.  Annals New York
    Academy of Sciences, 8/28/59; p.25.
16. Warburg, O. On the Origin of Cancer Cells, Science 123:309-14.
17. Beard, J. Enzyme Treatment of Cancer. London, Chalto and
    Windus, 1911.
18. Cancer Facts and Figures 1993. Publ. American Cancer Society.

December 15, 1994

NCI Sponsors Clinical Trial to Evaluate Program

     The National Cancer Institute will evaluate alternative methods that
have met the "best-case-series standards" (Contact Mary McCabe, RN, a
clinical trials specialist for NCI at 301-496-5583 for questions).  The
Kelley Program, developed by William Donald Kelley, DDS was used to heal
his own pancreatic cancer in 1967.  In a 17 year period, over 10,000
seriously ill patients were treated with this program.  Many were
terminally ill cancer patients, some still surviving as of this date. 
Nicholas Gonzales, MD, who conducted an exhaustive 5 year study of
Kelley's program, will conduct an initial 10 case pancreatic cancer trial. 
This is the subject of the NCI's interest.  Dr. Gonzales is presently
practicing his version of the Kelley method in New York.  The phone 
number I have for him is 212-213-3337.