Presented by THE ROBERT CATHEY RESEARCH SOURCE http://www.europa.com/~rsc ------------------------------------------------------------------------- panenzym.txt 97.01.09, AU:RSCathey This is just a note to inform the discretion of the reader who peruses these files looking for some relief for their cancer. You should know that no rigorous clinical study has been done in the United States that fully conforms to the regime suggested by various articles issuing from the RCRS. No claims are made for their effectiveness based on first hand experience, the true criterion for authority. However, the experience of qualified clinicians, MDs, biochemists and physiologists using similar protocols experimentally and therapeutically have attested to their effectiveness from their own first hand experience. Optimal protocols are of course a matter of extreme individuality, and best left to a qualified clinician most familiar with the individual's case. (We also have learned that the individual's own instincts and determination are often more sagacious and prophetic than the best clinical assessments or prognoses). Despite the long history established for these protocols (beginning with John Beard, 1902) there is much much more to learn. The interested reader should take recourse to such studies and determine for themselves the scientific foundations and applicability to their own condition. It is of course our view that these are factors pertaining to natural law, and therefore are invariant, and universally applicable. Other articles from other sources notwithstanding, it is believed that no program can be optimally effective that does not incorporate the entire gamut of pancreatic enzymes. All reports received from people who claim to have cured their cancer by eating apricot seeds alone nevertheless also were on mostly vegetarian diets, and raw foods, which would potentize the endogenous pancreatic enzyme complex, and superior nutrition provides for endogenous synthesis of these enzymes as well as strengthening the immune system. Trypsin or chymotrypsin treatment alone for cancer is not in conformity with the routine recommended for study by the RCRS. There is no rationale for use of proteolytic enzymes alone. It does not occur in nature, and has therefore no evolutionary precedent. Beard said such a program would not only not be effective, but dangerous. Beard also found that the protocol for the use of these enzymes should follow the ratio: proteolytic 1: glycolytic 2. Thus trypsin and chymotrypsin might be supplemented at 1,000 (or 10,000) units; amylase 2,000 (or 20,000)units. The extracts may be combined in a single syringe, but they should not be mixed for storage. Dr. Krebs and other authorities suggested the use of lyophilized preparations. Studies should be performed to measure the differences between enteric pH sensitive formulations against injected formulations; crystallized formulations against pancreatic extracts for injection. It is logical to have blood studies done for: __heavy metal ions or molecules and other metals known to be toxic (copper, mercury, silver, aluminum, etc.) and which deactivate the pancreatic enzymes. __parasitic anti-tryptic enzymes. __general protease inhibitor content of the serum (serpins). __biologically active chromium. __human chorionic gonadotropic hormone (hCG-holo, -Beta, Carboxy-terminal -peptide; hLH, etc.) __tyrosine __tyrosinase __amylase inhibiting or deactivating substances. Then studies should be performed for reactivating endogenous pancreatic enzymes: __nitrilosides (the hydrogen cyanide component reactivates trypsin as well as acting as an accelerator of proteolysis) __biologically active chromium (sources: brewer's yeast; black pepper) __magnesium sulfate (activates the zymogens of trypsin) __glutathione __hydrogen sulfide (hydrazine sulfate) (and others not yet studied) Pathways of co-factors important for pancreatic function: __Nitric Oxide Synthase(NOS) __L-arginine __sodium nitroprusside(SNP) __s-nitrocysteine(NO-CYS) __Acetylcholine (ACh..via NOS stimulation) Protocols for deactivating, conjugating or binding for removing inhibitors and toxins: __glucuronic acid __citric acid __malic acid __chelation therapy (EDTA, BAL, etc.) In the use of chelation, it also follows that a rigorous program to reconstitute the body with essential minerals in the form of chelates orotates, etc. should be followed. __Anti-parasitic programs (pancreatic enzymes and Laetrile are among the best anti-parasitic protocols) __Anti-oxidant protocols (again, the nitrilosides provide in HCN an ideal free radical scavenger) It is also a commonplace in herbal remedy regimens that one should first "clear a path" for the debris created by the destruction of the cancer. This is the rationale for bowel cleansing, liver cleansing, kidney cleansing, or flushes. Then the blood cleansing follows, and re-potentizing the enzymes and immune system. Naturally the primary way to achieve optimum serum conditions is through nutrition, which will also elevate the immune response. No single isolated compound, not even the Laetriles, which we believe to be the single most powerful extrinsic or dietary compounds in nature with specificity for the cancer cell, can conquer cancer. Even the laetriles (nitrilosides) require for their action the de-shielding of the pericellular negatively charged cancer glycoprotein coating by the pancreatic enzymes before the negatively charged cyanide ion can gain entrance to the cancer cytoplasm. However, since the freed hydrogen cyanide is an accelerator of proteolysis, it has obvious merit in any program at any stage addressing pancreatic insufficiency. Updated 01/01/97